What is Apigenin Extract?

Apigenin Extract is a high-quality source of apigenin (4',5,7-trihydroxyflavone), a naturally occurring aglycone flavonoid from the flavone subclass, standardized to a high concentration. It is generally extracted and isolated from the flowers of chamomile (Matricaria chamomilla), parsley (Petroselinum crispum), or citrus sources to produce a light yellow crystalline powder in varying purities (from 5% up to 98% HPLC). It is a stable, high-purity active ingredient, ideal for incorporation into nutraceutical dietary supplements, functional food and beverage formulations, personal care products, as well as cosmeceutical formulations, with a specific focus on procurement, product development, and formulation. The compound has several important chemical properties, such as a molecular weight of 270.24 g/mol (CAS 520-36-5) and outstanding intrinsic antioxidant activity, which ensures thermal and functional stability in various delivery matrix systems like capsules, tablets, skin serums, as well as applications in the skin conditioning field. Due to its organic solvent solubility and small particle size, it can be processed without any problems during the large-scale production of the product, blending, and encapsulation. Packaged in standard commercial bulk packaging (1 kg bags, etc and 25 kg fibre drums) with extended shelf-life stability. It is a plant-derived constituent that is reliable, ready-to-use, and can be used by global brand owners and OEM/ODM manufacturers for premium product innovations with a clean label.

Analysis

Market Trends

A macro-level paradigm shift toward clean label formulation, standardized natural sourcing, and innovation in plant-based ingredients is propelling the global market of plant bioactive constituents, especially in the nutraceutical, functional food, and cosmeceutical industry. Known for their plant origins, plant-derived compounds have become more attractive to consumers, leading to a growing trend for brand owners and finished-product manufacturers to look for transparency of the raw materials, traceability along the supply chain, and proof of the technical specifications. In the changing commercial environment, the procurement team and product development teams are increasingly interested in specialized phytochemical isolates, with Apigenin Powder becoming a major strategic player. Standardized flavones are increasingly being added to a variety of multi-ingredient formulations, nighttime lifestyle products, daily wellness blends, and advanced topical skin products in order to ensure precise ingredient levels without sacrificing batch consistency of the final product. Moreover, due to the strict documentation requirements established by the regulations, standardized bulk extract powders have become of great industrial value, with rigorous HPLC analytical testing, heavy metal screening, and third-party Quality Assurance compliance. With the expansion of portfolios for most international contract manufacturers and private label OEM/ODM companies, it is a versatile, stable, high-demand botanical raw material that is relevant to the macro consumer market's focus on clean label, bio-based solutions.

Features

As a physical and chemical product, it has unique properties that influence its use, stability, and incorporation into complex product formulations. It is a low molecular weight aglycone flavonoid (4',5,7-trihydroxyflavone, C15H10O5, MW: 270.24 g/mol) with a rigid planar polyphenol structure that has three reactive hydroxyl groups at the C-4', C-5, and C-7 positions, resulting in high radical scavenging properties and natural lipophilicity. Its high-purity commercial isolate form is presented as a light-yellow to greenish-yellow, odorless crystalline powder with high melting stability (345°C - 350°C), which is excellent for high-heat processing, hot-melt extrusion, and thermal tableting workflows. Parsley Extract Apigenin is insoluble in water at neutral pH (practically 0.001–0.003 mg/mL), but it is very soluble in polar organic solvents such as dimethyl sulfoxide (DMSO), ethanol, and alkylene glycols, and it has been solubilized by hydrophobic carrier matrices such as SMEDDS, liposomes, and complexation with cyclodextrins in alkaline aqueous systems. Its stable crystalline lattice necessitates special micronization or dispersion methods (usually 80-100 mesh pass rates) to achieve uniform blend homogeneity, to avoid sedimentation in its liquid suspension, and to ensure it is physically stable without degradation under normal ambient storage conditions, which are the most important concerns of formulation engineers.

Product Direction

1. Night-Time Lifestyle Capsules & Softgels

Apigenin Bulk Powder can be encapsulated and is included as a standardized active in clean-label evening routine and relaxation supplements with the addition of L-theanine or chamomile extract.

2. Photoprotective Serums & Facial Creams

It is incorporated at 0.1%–1.0% inclusion rates in topical formulations that take advantage of its antioxidant activity to protect skin from oxidative stress caused by the environment and maintain the elasticity of the skin.

3. Scalp Conditioners & Hair Root Tonics

In specialized hair care formulations, such as micro-emulsion scalp sprays and leave-in serums, apigenin is able to restore the balance of the scalp surface environment and condition the hair follicles.

4. Functional Beverage Powders & Stick-Packs

In micronized or water-dispersible form, manufacturers add it to ready-to-mix powdered teas, stick packs containing a blend of wellness ingredients, and instant evening drink powders.

5. Sublingual Botanical Drops & Tinctures

It is dissolved in a liquid form in lipid or glycol, which is then made into sublingual drops for quick absorption that can be added to non-pill dietary supplement lines.

6. Functional Gummies & Chewable Confections

Emulsified in a pectin matrix, it is an active that has been integrated into gummy or chewable formats that are easy to consume daily, for use by contract manufacturers.

FAQ

Q1: What raw material sources and purity grades are available for Apigenin Extract?

A: We provide Apigenin Extract from good-quality botanicals like Matricaria chamomilla in powder form, varying from 5% to 98% (HPLC) purity.

Q2: What is the solubility profile of Apigenin Extract for formulation development?

A: The solubility of apigenin is lipophilic; therefore, it is highly soluble in polar organic solvents such as DMSO and ethanol. In aqueous systems, complexation with cyclodextrins, the use of lipids as carriers, or the use of micronization can be used.

Q3: Is Apigenin Extract thermally stable for high-heat manufacturing processes?

A: Yes, apigenin is extremely suitable for thermal tableting, hot-melt tableting, and manufacturing of gummies, as it has an outstanding melting point range of 345°C-350°C.

Q4: What compliance and quality control documentation is provided with bulk orders?

A: Each batch comes with a complete Certificate of Analysis (COA) with HPLC assay purity, heavy metal screening, solvent residue analysis, and stringent microbiological compliance.

Q5: What are the standard commercial packaging options and Minimum Order Quantities (MOQ)?

A: The standard packaging specifications are 1kg aluminium foil bags for sample testing and 25kg fibre drums for bulk production – MOQs are flexible depending on the type of contract manufacturer.

Where to Buy Apigenin Powder?

To source Parsley Extract Apigenin of high quality, you may get directly into contact by simply mailing to info@scigroundbio.com, or you may fill in your requirements by filling the form at the bottom of our site.

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